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KMID : 1137820150360060241
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의공학회지
2015 Volume.36 No. 6 p.241 ~ p.250
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Temperature-Range-Dependent Optimization of Noninvasive MR Thermometry Methods
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Kim Jong-Min
Kumar Suchit
Jo Young-Seung
Park Hae-Kyung
Kim Jeong-Hee
Lee Chul-Hyun
Oh Chang-Hyun
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Abstract
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Noninvasive temperature monitoring is feasible with Magnetic Resonance Imaging (MRI) based on temperature sensitive MR parameters such as T1 and T2 relaxation times, Proton Resonance Frequency shift (PRFs), diffusion, exchange process, magnetization transfer contrast, chemical exchange saturation transfer, etc. While the temperature monitoring is very useful to guide the thermal treatment such as RF hyperthermia or thermal ablation, the optimization of the MR thermometry method is essential because the range of temperature measurement depends on the choice of the measurement methods. Useful temperature range depends on the purpose of treatment methods, for example, 42oC to 45oC for RF hyperthermia and over 50oC for thermal ablation. In this paper, MR thermometry methods using T1 and T2 relaxation times and PRFs-based MR thermometry are tried on a 3.0 T MRI system and their results are reported and compared. In addition, the scanning protocol and temperature calculation algorithms from T1 and T2 relaxation times and PRFs are optimized for the different temperature ranges for the purpose of RF hyperthermia and/or thermal ablation.
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KEYWORD
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Magnetic resonance imaging, Thermometry, Thermal therapy, Specific Absorption Rate, Proton Resonance Frequency Shift, T1, T2
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